T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells.

T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells.

HLA-E is a non-conventional MHC Class I molecule that has been recently demonstrated to present pathogen-derived ligands, resulting in the TCR-dependent activation of αβ CD8+ T cells. The goal of this study was to characterize the ligandome displayed by HLA-E following infection with Mycobacterium t...

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Bibliographic Details
Main Authors: Curtis McMurtrey, Melanie J Harriff, Gwendolyn M Swarbrick, Amanda Duncan, Meghan Cansler, Megan Null, Wilfried Bardet, Kenneth W Jackson, Deborah A Lewinsohn, William Hildebrand, David M Lewinsohn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5703486?pdf=render

Internet

http://europepmc.org/articles/PMC5703486?pdf=render

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