Simulated impact of RTS,S/AS01 vaccination programs in the context of changing malaria transmission.

INTRODUCTION: The RTS,S/AS01 pre-erythrocytic malaria vaccine is in phase III clinical trials. It is critical to anticipate where and how it should be implemented if trials are successful. Such planning may be complicated by changing levels of malaria transmission. METHODS/RESULTS: Computer simulati...

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Bibliographic Details
Main Authors: Alan Brooks, Olivier J T Briët, Diggory Hardy, Richard Steketee, Thomas A Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295753?pdf=render