MTNR1B Genetic Variability Is Associated with Gestational Diabetes in Czech Women

The gene MTNR1B encodes a receptor for melatonin. Melatonin receptors are expressed in human β-cells, which implies that genetic variants might affect glucose tolerance. Meta-analysis confirmed that the rs10830963 shows the most robust association. The aim of the study was to assess the rs10830963 i...

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Bibliographic Details
Main Authors: Daniela Vejrazkova, Petra Lukasova, Marketa Vankova, Josef Vcelak, Olga Bradnova, Veronika Cirmanova, Katerina Andelova, Hana Krejci, Bela Bendlova
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/508923