lncRNA 5430416N02Rik Promotes the Proliferation of Mouse Embryonic Stem Cells by Activating Mid1 Expression through 3D Chromatin Architecture

Summary: Both 3D chromatin architecture and long non-coding RNAs (lncRNAs) play essential roles in pluripotency maintenance. However, whether lncRNAs are involved in organizing 3D chromatin structure remains largely unexplored. We identified 39 lncRNAs bound by Klf4, among which we further revealed...

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Bibliographic Details
Main Authors: Tong Zhao, Mingyang Cai, Man Liu, Guangsong Su, Daniel An, Byoungsan Moon, Guochang Lyu, Yibo Si, Lingyi Chen, Wange Lu
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671120300588