Development of a novel recombinant ELISA for the detection of Crimean-Congo hemorrhagic fever virus IgG antibodies

Abstract Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral infection caused by Crimean-Congo hemorrhagic fever virus (CCHFV). Serological screening of CCHF is important and current ELISA use antigens prepared from virus which is expensive due to requirement of high bio-containment facilit...

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Bibliographic Details
Main Authors: Sultan Gülce-İz, Nazif Elaldı, Hüseyin Can, Esra Atalay Şahar, Muhammet Karakavuk, Aytül Gül, Gizem Örs Kumoğlu, Aysu Değirmenci Döşkaya, Adnan Yüksel Gürüz, Aykut Özdarendeli, Philip Louis Felgner, Huw Davies, Mert Döşkaya
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85323-1