100 Hz Electroacupuncture Alleviated Chronic Itch and GRPR Expression Through Activation of Kappa Opioid Receptors in Spinal Dorsal Horn

100 Hz Electroacupuncture Alleviated Chronic Itch and GRPR Expression Through Activation of Kappa Opioid Receptors in Spinal Dorsal Horn

BackgroundClinical studies have shown that electroacupuncture (EA) alleviates chronic itch. Gastrin-releasing peptide receptor (GRPR) and dynorphin (DYN) in the spinal dorsal horn positively or negatively regulate itch, respectively. However, which frequency of EA is effective on relieving chronic i...

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Bibliographic Details
Main Authors: Hong-Ping Li, Xiao-Yu Wang, Chao Chen, Jing-Jing Li, Chi Yu, Li-Xue Lin, Zi-E Yu, Zhi-Yuan Jin, He Zhu, Hong-Chun Xiang, Xue-Fei Hu, Jie Cao, Xiang-Hong Jing, Man Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
EA
chronic itch
spontaneous scratching
GRPR
DYN-A
kappa opioid receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.625471/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.625471/full

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