Seno-destructive smooth muscle cells in the ascending aorta of patients with bicuspid aortic valve diseaseResearch in context

Background: Ascending aortic aneurysms constitute an important hazard for individuals with a bicuspid aortic valve (BAV). However, the processes that degrade the aortic wall in BAV disease remain poorly understood. Methods: We undertook in situ analysis of ascending aortas from 68 patients, seeking...

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Bibliographic Details
Main Authors: Brittany Balint, Hao Yin, Zengxuan Nong, John-Michael Arpino, Caroline O'Neil, Stephanie R. Rogers, Varinder K. Randhawa, Stephanie A. Fox, Jacqueline Chevalier, Jason J. Lee, Michael W.A. Chu, J. Geoffrey Pickering
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302993