Instability of the octarepeat region of the human prion protein gene.

Prion diseases are a family of unique fatal transmissible neurodegenerative diseases that affect humans and many animals. Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease in humans, accounting for 85-90% of all human prion cases, and exhibits a high degree of diversity in p...

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Bibliographic Details
Main Authors: Baiya Li, Liuting Qing, Jianqun Yan, Qingzhong Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197570?pdf=render