Protective role of Gentianella acuta on isoprenaline induced myocardial fibrosis in rats via inhibition of NF-κB pathway

Protective role of Gentianella acuta on isoprenaline induced myocardial fibrosis in rats via inhibition of NF-κB pathway

Gentianella acuta (Michx.) Hulten (G. acuta) has been widely used in Mongolian medicines for the treatment of cardiovascular diseases in Ewenki and Oroqen, Inner Mongolia autonomous region, China. The aim of this study was to investigate the effects and related mechanism of G. acuta on isoproterenol...

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Bibliographic Details
Main Authors: Ai-Ying Li, Jing-Jing Wang, Sheng-Chang Yang, Ya-Shuo Zhao, Jie-Ru Li, Yu Liu, Jia-Huan Sun, Li-Ping An, Peng Guan, En-Sheng Ji
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Gentianella acuta
Myocardial fibrosis
NF-κB
TGF-β1
Collagen
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218369981

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http://www.sciencedirect.com/science/article/pii/S0753332218369981

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