Specific inhibitors of urokinase plasminogen activator for treatment of cancers; In silico approach

Invasion, metastasis and angiogenesis are fundamental processes in the development of solid cancers. All these depend on the proteolysis where plasminogen activation system (PAS) is the prominent component. Plasmin of PAS, with a broad spectrum of proteins lysed, is secreted as a pro-enzyme and the...

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Bibliographic Details
Main Authors: Benjamin Talbot, Jerzy Jankun
Format: Article
Language:English
Published: The University of Toledo 2020-05-01
Series:Translation
Subjects:
Online Access:https://openjournals.utoledo.edu/index.php/translation/article/view/346