The Associations between COMT and MAO-B Genetic Variants with Negative Symptoms in Patients with Schizophrenia

The Associations between COMT and MAO-B Genetic Variants with Negative Symptoms in Patients with Schizophrenia

Negative symptoms of schizophrenia, including anhedonia, represent a heavy burden on patients and their relatives. These symptoms are associated with cortical hypodopamynergia and impaired striatal dopamine release in response to reward stimuli. Catechol-O-methyltransferase (COMT) and monoamine oxid...

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Bibliographic Details
Main Authors: Zoran Madzarac, Lucija Tudor, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Nela Pivac
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Current Issues in Molecular Biology
Subjects:
alogia
anhedonia
COMT
MAO-B
negative symptoms
patients
Online Access:https://www.mdpi.com/1467-3045/43/2/45

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https://www.mdpi.com/1467-3045/43/2/45

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