A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease

While astrocytes, the most abundant cells found in the brain, have many diverse functions, their role in the lysosomal storage disorder Gaucher disease (GD) has not been explored. GD, resulting from the inherited deficiency of the enzyme glucocerebrosidase and subsequent accumulation of glucosylcera...

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Bibliographic Details
Main Authors: Elma Aflaki, Barbara K. Stubblefield, Ryan P. McGlinchey, Benjamin McMahon, Daniel S. Ory, Ellen Sidransky
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303225