Conversion to Everolimus was Beneficial and Safe for Fast and Slow Tacrolimus Metabolizers after Renal Transplantation

Conversion to Everolimus was Beneficial and Safe for Fast and Slow Tacrolimus Metabolizers after Renal Transplantation

Fast tacrolimus (TAC) metabolism (concentration/dose (C/D) ratio <1.05 ng/mL/mg) is a risk factor for inferior outcomes after renal transplantation (RTx) as it fosters, e.g., TAC-related nephrotoxicity. TAC minimization or conversion to calcineurin-inhibitor free immunosuppression are strateg...

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Bibliographic Details
Main Authors: Gerold Thölking, Nils Hendrik Gillhaus, Katharina Schütte-Nütgen, Hermann Pavenstädt, Raphael Koch, Barbara Suwelack, Stefan Reuter
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Journal of Clinical Medicine
Subjects:
tacrolimus
c/d ratio
tacrolimus metabolism
everolimus
conversion
kidney transplantation
Online Access:https://www.mdpi.com/2077-0383/9/2/328

Internet

https://www.mdpi.com/2077-0383/9/2/328

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