Retained PTEN Expression Preferentially Identifies Mismatch Repair-Proficient Breast Cancers
Introduction/ Background Loss of phosphatase and tensin homolog (PTEN) expression and alterations in mismatch repair (MMR) genes are regarded as early oncogenic events in breast cancer. It has recently been hypothesized that the polyadenosine tract in PTEN might be a target for mutation in MMR-defic...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
DiagnomX
2016-06-01
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Series: | Diagnostic Pathology |
Online Access: | http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/191 |