Retained PTEN Expression Preferentially Identifies Mismatch Repair-Proficient Breast Cancers

Introduction/ Background Loss of phosphatase and tensin homolog (PTEN) expression and alterations in mismatch repair (MMR) genes are regarded as early oncogenic events in breast cancer. It has recently been hypothesized that the polyadenosine tract in PTEN might be a target for mutation in MMR-defic...

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Bibliographic Details
Main Authors: Nicola Fusco, L. Runza, G. Ercoli, D. Gambini, C. Blundo, L. Despini, M. Giroda, S. Bosari
Format: Article
Language:English
Published: DiagnomX 2016-06-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/191