Costs and Benefits of Mutational Robustness in RNA Viruses

The accumulation of mutations in RNA viruses is thought to facilitate rapid adaptation to changes in the environment. However, most mutations have deleterious effects on fitness, especially for viruses. Thus, tolerance to mutations should determine the nature and extent of genetic diversity that can...

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Bibliographic Details
Main Authors: Adi Stern, Simone Bianco, Ming Te Yeh, Caroline Wright, Kristin Butcher, Chao Tang, Rasmus Nielsen, Raul Andino
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714005786