Immunogenicity of bivalent human papillomavirus DNA vaccine using human endogenous retrovirus envelope-coated baculoviral vectors in mice and pigs.

Immunogenicity of bivalent human papillomavirus DNA vaccine using human endogenous retrovirus envelope-coated baculoviral vectors in mice and pigs.

Human papillomavirus is known to be the major pathogen of cervical cancer. Here, we report the efficacy of a bivalent human papillomavirus type 16 and 18 DNA vaccine system following repeated dosing in mice and pigs using a recombinant baculovirus bearing human endogenous retrovirus envelope protein...

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Bibliographic Details
Main Authors: Hee-Jung Lee, Yoon-Ki Hur, Youn-Dong Cho, Mi-Gyeong Kim, Hoon-Taek Lee, Yu-Kyoung Oh, Young Bong Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3507738?pdf=render

Internet

http://europepmc.org/articles/PMC3507738?pdf=render

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