The effects of mechanical stress on the growth, differentiation, and paracrine factor production of cardiac stem cells.

Stem cell therapies have been clinically employed to repair the injured heart, and cardiac stem cells are thought to be one of the most potent stem cell candidates. The beating heart is characterized by dynamic mechanical stresses, which may have a significant impact on stem cell therapy. The purpos...

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Bibliographic Details
Main Authors: Hiroshi Kurazumi, Masayuki Kubo, Mako Ohshima, Yumi Yamamoto, Yoshihiro Takemoto, Ryo Suzuki, Shigeru Ikenaga, Akihito Mikamo, Koichi Udo, Kimikazu Hamano, Tao-Sheng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3247223?pdf=render