Insight of the cytotoxicity of the aggregates of peptides or aberrant proteins: a meta-analysis.

Aberrant proteins or peptide aggregates form soluble oligomers or nanofibrils that can cause a wide range of amyloidosis diseases, including Alzheimer's disease (AD). The mechanisms of their cytotoxicity, however, remain controversial and poorly understood, greatly hindering the development of...

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Bibliographic Details
Main Authors: Rong Zhou, Bing Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4000214?pdf=render