Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization

Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization

Rebecca L Ball,1 Palak Bajaj,1,2 Kathryn A Whitehead1,2 1Department of Chemical Engineering, 2Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA Abstract: The broadest clinical application of siRNA therapeutics will be facilitated by drug-loaded delivery systems...

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Bibliographic Details
Main Authors: Ball RL, Bajaj P, Whitehead KA
Format: Article
Language:English
Published: Dove Medical Press 2016-12-01
Series:International Journal of Nanomedicine
Subjects:
Lipid nanoparticles
nanoparticle stability
lyophilization
lyoprotectants
nanoparticle storage
siRNA delivery
Online Access:https://www.dovepress.com/achieving-long-term-stability-of-lipid-nanoparticles-examining-the-eff-peer-reviewed-article-IJN

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https://www.dovepress.com/achieving-long-term-stability-of-lipid-nanoparticles-examining-the-eff-peer-reviewed-article-IJN

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