Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-Beta or Carboxyl Esterase on the Growth of LNCaP Prostate Cancer Cells

Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-Beta or Carboxyl Esterase on the Growth of LNCaP Prostate Cancer Cells

The risk of prostate cancer has been increasing in men by degrees. To develop a new prostate cancer therapy, we used a stem cell-derived gene directed prodrug enzyme system using human neural stem cells (hNSCs) that have a tumor-tropic effect. These hNSCs were transduced with the therapeutic genes f...

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Bibliographic Details
Main Authors: Kyung-Chul Choi, Seung U. Kim, Kyung-A. Hwang, Yun-Bae Kim, Bo-Rim Yi
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:International Journal of Molecular Sciences
Subjects:
human stem cells
prostate cancer
cytosine deaminase
interferon-beta
carboxyl esterase
tumor-tropism
Online Access:http://www.mdpi.com/1422-0067/13/10/12519

Internet

http://www.mdpi.com/1422-0067/13/10/12519

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