HIV-1 infection of bone marrow hematopoietic progenitor cells and their role in trafficking and viral dissemination.

Patients with HIV-1 often present with a wide range of hematopoietic abnormalities, some of which may be due to the presence of opportunistic infections and to therapeutic drug treatments. However, many of these abnormalities are directly related to HIV-1 replication in the bone marrow (BM). Althoug...

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Bibliographic Details
Main Authors: Aikaterini Alexaki, Brian Wigdahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2603331?pdf=render