The structural basis of proton driven zinc transport by ZntB

The bacterial zinc transporter ZntB is important for maintaining zinc homeostasis and is mechanistically not well understood. Here, the authors present the cryo-EM structure of ZntB at 4.2 Å resolution, perform transport assays and propose a model for its Zn2+ transport mechanism.

Bibliographic Details
Main Authors: Cornelius Gati, Artem Stetsenko, Dirk J. Slotboom, Sjors H. W. Scheres, Albert Guskov
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01483-7