Characterization of immune responses induced by immunization with the HA DNA vaccines of two antigenically distinctive H5N1 HPAIV isolates.

Characterization of immune responses induced by immunization with the HA DNA vaccines of two antigenically distinctive H5N1 HPAIV isolates.

The evolution of the H5N1 highly pathogenic avian influenza virus (HPAIV) has resulted in high sequence variations and diverse antigenic properties in circulating viral isolates. We investigated immune responses induced by HA DNA vaccines of two contemporary H5N1 HPAIV isolates, A/bar-headed goose/Q...

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Bibliographic Details
Main Authors: Yulong Gao, Zhiyuan Wen, Ke Dong, Gongxun Zhong, Xiaomei Wang, Zhigao Bu, Hualan Chen, Ling Ye, Chinglai Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409192?pdf=render

Internet

http://europepmc.org/articles/PMC3409192?pdf=render

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