Metabolic benefits of inhibition of p38α in white adipose tissue in obesity.

Metabolic benefits of inhibition of p38α in white adipose tissue in obesity.

p38 has long been known as a central mediator of protein kinase A (PKA) signaling in brown adipocytes, which positively regulate the transcription of uncoupling protein 1 (UCP-1). However, the physiological role of p38 in adipose tissues, especially the white adipose tissue (WAT), is largely unknown...

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Bibliographic Details
Main Authors: Shengjie Zhang, Hongchao Cao, Yan Li, Yanyan Jing, Shengnan Liu, Cheng Ye, Hui Wang, Shuxian Yu, Chengyuan Peng, Lijian Hui, Yu-Cheng Wang, Haibing Zhang, Feifan Guo, Qiwei Zhai, Ruimin Huang, Ling Zhang, Jingjing Jiang, Wei Liu, Hao Ying
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2004225

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https://doi.org/10.1371/journal.pbio.2004225

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