Structural Basis of Targeting the Exportin CRM1 in Cancer

Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly regulated and coordinated, involving different nuclear transport factors or receptors, importins and exportins, that med...

Full description

Bibliographic Details
Main Authors: Achim Dickmanns, Thomas Monecke, Ralf Ficner
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Cells
Subjects:
NES
Online Access:http://www.mdpi.com/2073-4409/4/3/538