Differential effects on neurodevelopment of FTO variants in obesity and bipolar disorder suggested by in silico prediction of functional impact: An analysis in Mexican population

Differential effects on neurodevelopment of FTO variants in obesity and bipolar disorder suggested by in silico prediction of functional impact: An analysis in Mexican population

Abstract Introduction Several studies indicate that polygenic obesity is linked to fat‐mass and obesity‐associated (FTO) genetic variants. Nevertheless, the link between variants in FTO and mental disorders has been barely explored. The present work aims to determine whether FTO genetic variants are...

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Bibliographic Details
Main Authors: Erasmo Saucedo‐Uribe, Alma Delia Genis‐Mendoza, Adriana Díaz‐Anzaldúa, José Jaime Martínez‐Magaña, Carlos Alfonso Tovilla‐Zarate, Isela Juárez‐Rojop, Nuria Lanzagorta, Michael Escamilla, Thelma Beatriz González‐Castro, María Lilia López Narvaez, Yazmín Hernández‐Díaz, Humberto Nicolini
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Brain and Behavior
Subjects:
bipolar disorder
FTO variants
in silico functional prediction
neurodevelopment
Online Access:https://doi.org/10.1002/brb3.1249

Internet

https://doi.org/10.1002/brb3.1249

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