The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission

The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission

Abstract Two members of 6-cysteine (6-cys) protein family, P48/45 and P230, are important for gamete fertility in rodent and human malaria parasites and are leading transmission blocking vaccine antigens. Rodent and human parasites encode a paralog of P230, called P230p. While P230 is expressed in m...

Full description

Bibliographic Details
Main Authors: Catherin Marin-Mogollon, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Fiona J. A. van Pul, Jai Ramesar, Ahmad Syibli Othman, Hans Kroeze, Jun Miao, Liwang Cui, Kim C. Williamson, Robert W. Sauerwein, Chris J. Janse, Shahid M. Khan
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Male Gametocytes
Ookinete Formation
Mosquito Transmission
Exflagellation Centres
Oocysts
Online Access:https://doi.org/10.1038/s41598-018-33236-x

Internet

https://doi.org/10.1038/s41598-018-33236-x

Similar Items