Heat shock pretreatment of mesenchymal stem cells for inhibiting the apoptosis of ovarian granulosa cells enhanced the repair effect on chemotherapy-induced premature ovarian failure

Heat shock pretreatment of mesenchymal stem cells for inhibiting the apoptosis of ovarian granulosa cells enhanced the repair effect on chemotherapy-induced premature ovarian failure

Abstract Background Premature ovarian failure (POF) is a severe complication associated with chemotherapy for female patients of childbearing age. A previous study has shown that bone marrow-derived mesenchymal stem cells (MSCs) can partially repair the damaged ovarian structure and function followi...

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Bibliographic Details
Main Authors: Xiaoying Chen, Qing Wang, Xinran Li, Qingru Wang, Jiaxin Xie, Xiafei Fu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Stem Cell Research & Therapy
Subjects:
Heat shock
Bone marrow-derived mesenchymal stem cells
Premature ovarian failure
Chemotherapy
Online Access:http://link.springer.com/article/10.1186/s13287-018-0964-4

Internet

http://link.springer.com/article/10.1186/s13287-018-0964-4

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