An In-Silico Pipeline for Rapid Screening of DNA Aptamers against Mycotoxins: The Case-Study of Fumonisin B1, Aflatoxin B1 and Ochratoxin A

An In-Silico Pipeline for Rapid Screening of DNA Aptamers against Mycotoxins: The Case-Study of Fumonisin B1, Aflatoxin B1 and Ochratoxin A

Aptamers are single-stranded oligonucleotides selected by SELEX (Systematic Evolution of Ligands by EXponential Enrichment) able to discriminate target molecules with high affinity and specificity, even in the case of very closely related structures. Aptamers have been produced for several targets i...

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Bibliographic Details
Main Authors: Fulvio Ciriaco, Vincenzo De Leo, Lucia Catucci, Michelangelo Pascale, Antonio F. Logrieco, Maria C. DeRosa, Annalisa De Girolamo
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Polymers
Subjects:
ssDNA aptamers
in-silico approach
binding affinity
mycotoxins
fumonisin B1
aflatoxin B1
Online Access:https://www.mdpi.com/2073-4360/12/12/2983

Internet

https://www.mdpi.com/2073-4360/12/12/2983

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