A mini-review on Biginelli adducts with notable pharmacological properties

A mini-review on Biginelli adducts with notable pharmacological properties

Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs) have emerged as prototypes for the design of compounds with a broad variety of biological activities. This mini-review describes over 100 Biginelli adducts demon...

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Bibliographic Details
Main Authors: Ângelo de Fátima, Taniris C. Braga, Leonardo da S. Neto, Bruna S. Terra, Breno G.F. Oliveira, Daniel L. da Silva, Luzia V. Modolo
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Journal of Advanced Research
Subjects:
Biginelli adducts
Antiproliferative activity cancer
Calcium channel
Antimicrobial activity
Antioxidants
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123214001295

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http://www.sciencedirect.com/science/article/pii/S2090123214001295

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