Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.

Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.

The T-box transcription factor TBX18 is essential to mesenchymal cell differentiation in several tissues and Tbx18 loss-of-function results in dramatic organ malformations and perinatal lethality. Here we demonstrate for the first time that Tbx18 is required for the normal development of periductal...

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Bibliographic Details
Main Authors: C Chase Bolt, Soumya Negi, Nuno Guimarães-Camboa, Huimin Zhang, Joseph M Troy, Xiaochen Lu, Andreas Kispert, Sylvia M Evans, Lisa Stubbs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4847854?pdf=render

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http://europepmc.org/articles/PMC4847854?pdf=render

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