Development and validation of an immune checkpoint-based signature to predict prognosis in nasopharyngeal carcinoma using computational pathology analysis

Development and validation of an immune checkpoint-based signature to predict prognosis in nasopharyngeal carcinoma using computational pathology analysis

Abstract Background Immunotherapy, especially immune checkpoint inhibition, has provided powerful tools against cancer. We aimed to detect the expression of common immune checkpoints and evaluate their prognostic values in nasopharyngeal carcinoma (NPC). Methods The expression of 9 immune checkpoint...

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Bibliographic Details
Main Authors: Ya-Qin Wang, Yu Zhang, Wei Jiang, Yu-Pei Chen, Shuo-Yu Xu, Na Liu, Yin Zhao, Li Li, Yuan Lei, Xiao-Hong Hong, Ye-Lin Liang, Jun-Yan Li, Lu-Lu Zhang, Jing-Ping Yun, Ying Sun, Ying-Qin Li, Jun Ma
Format: Article
Language:English
Published: BMJ Publishing Group 2019-11-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Immune checkpoint-based signature
Nasopharyngeal carcinoma
Computational pathology analysis
Tumour-immune microenvironment
EBV-DNA
Online Access:http://link.springer.com/article/10.1186/s40425-019-0752-4

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http://link.springer.com/article/10.1186/s40425-019-0752-4

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