Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.

Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.

Most West Nile virus (WNV) infections are asymptomatic, but some lead to neuroinvasive disease with symptoms ranging from disorientation to paralysis and death. Evidence from animal models suggests that neuroinvasive infections may arise as a consequence of impaired immune protection. However, other...

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Bibliographic Details
Main Authors: Eddie A James, Theresa J Gates, Rebecca E LaFond, Shinobu Yamamoto, Chester Ni, Duy Mai, Vivian H Gersuk, Kimberly O'Brien, Quynh-Anh Nguyen, Brad Zeitner, Marion C Lanteri, Philip J Norris, Damien Chaussabel, Uma Malhotra, William W Kwok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005375

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https://doi.org/10.1371/journal.ppat.1005375

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