Determination of SFRP1 and SFRP2 Genes Promoter Methylation Status in Patients with Chronic Myelogenous Leukemia

Background and Aim: Chronic myeloid leukemia (CML) is a myeloprolifrative neoplasm that is characterized by an expansion of myeloid, erythroid cells and platelets in peripheral blood and myeloid hyperplasia in bone marrow. Secreted frizzled-related protein family is a negative regulator of the Wnt s...

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Bibliographic Details
Main Authors: Elahe Derakhshanfar, Shaban Alizadeh, Hassan Rafiemehr, Fateme Nadali, Ali Qasemi, Masuod Karimi, Nushin Shabab
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2017-03-01
Series:پیاورد سلامت
Subjects:
Online Access:http://payavard.tums.ac.ir/article-1-6144-en.html