IL-17A mediates early post-transplant lesions after heterotopic trachea allotransplantation in Mice.

Primary graft dysfunction (PGD) and bronchiolitis obliterans (BO) are the leading causes of morbidity and mortality after lung transplantation. Reports from clinical and rodent models suggest the implication of IL-17A in either PGD or BO. We took advantage of the heterotopic trachea transplantation...

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Bibliographic Details
Main Authors: Philippe H Lemaître, Benoît Vokaer, Louis-Marie Charbonnier, Yoichiro Iwakura, Marc Estenne, Michel Goldman, Oberdan Leo, Myriam Remmelink, Alain Le Moine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728020?pdf=render