Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling.

CXCL12 (SDF-1) is a chemokine that binds to and signals through the seven transmembrane receptor CXCR4. The CXCL12/CXCR4 signaling axis has been implicated in both cancer metastases and human immunodeficiency virus type 1 (HIV-1) infection and a more complete understanding of CXCL12/CXCR4 signaling...

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Bibliographic Details
Main Authors: Jason A Wojcechowskyj, Jessica Y Lee, Steven H Seeholzer, Robert W Doms
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3176801?pdf=render