Bisphenol A alters n-6 fatty acid composition and decreases antioxidant enzyme levels in rat testes: a LC-QTOF-based metabolomics study.

BACKGROUND: Male reproductive toxicity induced by exposure to bisphenol A (BPA) has been widely reported. The testes have proven to be a major target organ of BPA toxicity, so studying testicular metabolite variation holds promise for the discovery of mechanisms linked to the toxic effects of BPA on...

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Main Authors: Minjian Chen, Bin Xu, Wenliang Ji, Shanlei Qiao, Nan Hu, Yanhui Hu, Wei Wu, Lianglin Qiu, Ruyang Zhang, Yubang Wang, Shoulin Wang, Zuomin Zhou, Yankai Xia, Xinru Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3443100?pdf=render