Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells

Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells

Inflammation is a primary component of both initiation and promotion of colorectal cancer (CRC). Cytokines secreted by macrophages, including tumor necrosis factor alpha (TNFα), activates the pro-survival transcription factor complex NFκB. The precise mechanism of NFκB in CRC is not well studied, bu...

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Bibliographic Details
Main Authors: Rajitha Indukuri, Linnea Hases, Amena Archer, Cecilia Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
p65
ERβ
ChIP
colon cancer
colorectal cancer (CRC)
estrogen receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.650625/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.650625/full

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