Wear of hip prostheses increases serum IGFBP-1 levels in patients with aseptic loosening

Abstract The biological mechanisms involved in aseptic loosening include inflammation-associated and bone resorption-associated processes. Coordinated cellular actions result in biochemical imbalances with devastating consequences for the joint. Given that this condition is not known for showing sys...

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Bibliographic Details
Main Authors: Gema Vallés, Eduardo García-Rey, Laura Saldaña, Eduardo García-Cimbrelo, Nuria Vilaboa
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79813-x