TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2

TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2

Nrf1 and Nrf2, as two principal CNC-bZIP transcription factors, regulate similar but different targets involved in a variety of biological functions for maintaining cell homeostasis and organ integrity. Of note, the unique topobiological behavior of Nrf1 makes its functions more complicated than Nrf...

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Bibliographic Details
Main Authors: Meng Wang, Yonggang Ren, Shaofan Hu, Keli Liu, Lu Qiu, Yiguo Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
TCF11
Nrf1α
Nrf2
transcriptomic sequencing
regulatory profiling
hepatocellular carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.707032/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.707032/full

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