Distinct Molecular Signatures of Quiescent and Activated Adult Neural Stem Cells Reveal Specific Interactions with Their Microenvironment

Summary: Deciphering the mechanisms that regulate the quiescence of adult neural stem cells (NSCs) is crucial for the development of therapeutic strategies based on the stimulation of their endogenous regenerative potential in the damaged brain. We show that LeXbright cells sorted from the adult mou...

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Bibliographic Details
Main Authors: Lise Morizur, Alexandra Chicheportiche, Laurent R. Gauthier, Mathieu Daynac, François D. Boussin, Marc-André Mouthon
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118302686