Borrowing Nuclear DNA Helicases to Protect Mitochondrial DNA
In normal cells, mitochondria are the primary organelles that generate energy, which is critical for cellular metabolism. Mitochondrial dysfunction, caused by mitochondrial DNA (mtDNA) mutations or an abnormal mtDNA copy number, is linked to a range of human diseases, including Alzheimer’s disease,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1422-0067/16/5/10870 |