Anti-Tumor Effects of an Oncolytic Adenovirus Expressing Hemagglutinin-Neuraminidase of Newcastle Disease Virus in Vitro and in Vivo

Anti-Tumor Effects of an Oncolytic Adenovirus Expressing Hemagglutinin-Neuraminidase of Newcastle Disease Virus in Vitro and in Vivo

Oncolytic virotherapy has been an attractive drug platform for targeted therapy of cancer over the past few years. Viral vectors can be used to target and lyse cancer cells, but achieving good efficacy and specificity with this treatment approach is a major challenge. Here, we assessed the ability o...

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Bibliographic Details
Main Authors: Dongyun He, Lili Sun, Chang Li, Ningning Hu, Yuan Sheng, Zhifei Chen, Xiao Li, Baorong Chi, Ningyi Jin
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Viruses
Subjects:
anti-tumor
hemagglutinin-neuraminidase gene
apoptosis
oncolytic adenoviruses
esophageal cancer
Online Access:http://www.mdpi.com/1999-4915/6/2/856

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http://www.mdpi.com/1999-4915/6/2/856

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