Down Modulation of Host Immune Response by Amino Acid Repeats Present in a Trypanosoma cruzi Ribosomal Antigen

Down Modulation of Host Immune Response by Amino Acid Repeats Present in a Trypanosoma cruzi Ribosomal Antigen

Several antigens from Trypanosoma cruzi, the causative agent of Chagas disease (CD), contain amino acid repeats identified as targets of the host immune response. Ribosomal proteins containing an Ala, Lys, Pro-rich repeat domain are among the T. cruzi antigens that are strongly recognized by antibod...

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Bibliographic Details
Main Authors: Carlos A. Toro Acevedo, Bruna M. Valente, Gabriela A. Burle-Caldas, Bruno Galvão-Filho, Helton da C. Santiago, Rosa M. Esteves Arantes, Caroline Junqueira, Ricardo T. Gazzinelli, Ester Roffê, Santuza M. R. Teixeira
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
Trypanosoma cruzi
immune response
B-cell
immunomodulation
virulence factors
antigen
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02188/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02188/full

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