DNA Targeting Sequence Improves Magnetic Nanoparticle-Based Plasmid DNA Transfection Efficiency in Model Neurons

DNA Targeting Sequence Improves Magnetic Nanoparticle-Based Plasmid DNA Transfection Efficiency in Model Neurons

Efficient non-viral plasmid DNA transfection of most stem cells, progenitor cells and primary cell lines currently presents an obstacle for many applications within gene therapy research. From a standpoint of efficiency and cell viability, magnetic nanoparticle-based DNA transfection is a promising...

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Bibliographic Details
Main Authors: Matthew M. Vernon, David A. Dean, Jon Dobson
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
DNA targeting sequence
gene transfection
magnetic nanoparticles
neuroblastoma
nuclear localization
primary neurons
plasmid DNA
SH-SY5Y cells
Online Access:http://www.mdpi.com/1422-0067/16/8/19369

Internet

http://www.mdpi.com/1422-0067/16/8/19369

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