Role of the vacuolar ATPase in the Alphavirus replication cycle

We have shown that Alphaviruses can enter cells by direct penetration at the plasma membrane (R. Vancini, G. Wang, D. Ferreira, R. Hernandez, and D. Brown, J Virol, 87:4352–4359, 2013). Direct penetration removes the requirement for receptor-mediated endocytosis exposure to low pH and membrane fusio...

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Bibliographic Details
Main Authors: Ryan M. Schuchman, Ricardo Vancini, Amanda Piper, Denitra Breuer, Mariana Ribeiro, Davis Ferreira, Joseph Magliocca, Veronica Emmerich, Raquel Hernandez, Dennis T. Brown
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018324307