Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank

Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank

Background: Epidemiological studies report increased comorbidity between depression and autoimmune diseases. The role of shared genetic influences in the observed comorbidity is unclear. We investigated the evidence for pleiotropy between these traits in the UK Biobank (UKB). Methods: We defined aut...

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Bibliographic Details
Main Authors: Kylie P. Glanville, Jonathan R.I. Coleman, Paul F. O'Reilly, James Galloway, Cathryn M. Lewis
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biological Psychiatry Global Open Science
Subjects:
Autoimmune diseases
Depression
Genetics
Pleiotropy
Autoimmune diseases, Depression, Genetics, Pleiotropy, UK Biobank
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174321000045

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http://www.sciencedirect.com/science/article/pii/S2667174321000045

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