INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions

INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions

Analysis of sites of newly integrated DNA in cellular genomes is important to several fields, but methods for analyzing and visualizing these datasets are still under development. Here, we describe tools for data analysis and visualization that take as input integration site data from our INSPIIRED...

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Bibliographic Details
Main Authors: Charles C. Berry, Christopher Nobles, Emmanuelle Six, Yinghua Wu, Nirav Malani, Eric Sherman, Anatoly Dryga, John K. Everett, Frances Male, Aubrey Bailey, Kyle Bittinger, Mary J. Drake, Laure Caccavelli, Paul Bates, Salima Hacein-Bey-Abina, Marina Cavazzana, Frederic D. Bushman
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
lentivirus
gene therapy
vector
SCID-X1
gammaretrovirus
retrovirus
insertional mutagenesis
vector driving
mutagenesis
recombination
data visualization
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116301310

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http://www.sciencedirect.com/science/article/pii/S2329050116301310

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