miR-138-5p induces aggressive traits by targeting Trp53 expression in murine melanoma cells, and correlates with poor prognosis of melanoma patients

miR-138-5p induces aggressive traits by targeting Trp53 expression in murine melanoma cells, and correlates with poor prognosis of melanoma patients

Deregulation of miRNAs contributes to the development of distinct cancer types, including melanoma, an aggressive form of skin cancer characterized by high metastatic potential and poor prognosis. The expression of a set of 580 miRNAs was investigated in a model of murine melanoma progression, compr...

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Bibliographic Details
Main Authors: Adriana Taveira da Cruz, Aline Hunger, Fabiana Henriques Machado de Melo, Ana Carolina Monteiro, Geneviève Catherine Paré, Dulce Lai, Débora Kristina Alves-Fernandes, Ana Luisa Pedroso Ayub, Esteban Mauricio Cordero, José Franco da Silveira Filho, Regine Schneider-Stock, Bryan Eric Strauss, Victor Tron, Miriam Galvonas Jasiulionis
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Melanoma
miR-138-5p
Trp53
Metastasis
Aggressiveness
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000415

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http://www.sciencedirect.com/science/article/pii/S1476558621000415

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