Multifunctional role of Bcl-2 in malignant transformation and tumorigenesis of Cr(VI)-transformed lung cells.

B-cell lymphoma-2 (Bcl-2) is an antiapoptotic protein known to be important in the regulation of apoptosis in various cell types. However, its role in malignant transformation and tumorigenesis of human lung cells is not well understood. We previously reported that chronic exposure of human lung epi...

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Bibliographic Details
Main Authors: Djordje Medan, Sudjit Luanpitpong, Neelam Azad, Liying Wang, Bing-Hua Jiang, Mary E Davis, John B Barnett, Lan Guo, Yon Rojanasakul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3362580?pdf=render